No way! / Not at all! / Come off it!
Strong informal denial or disagreement. ¡Qué va! = no way / absolutely not / not a chance. Very Spanish — has no direct English equivalent.
—Did you like the film? —No way! It was boring.
—Are you tired? —Not at all! I could go on all night.
Come off it! That's not what happened.
—Did you like the movie? —No way, it was horrible!
Am I tired? Not at all!