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Se lo agradezco en el alma

I'm deeply grateful / I thank you from the bottom of my heart

Politeness Phrases
Notes & Usage:

Very heartfelt and emotional expression of gratitude. Used when someone has done something truly significant for you.

See It in Context

Se lo agradezco en el alma, no sé cómo pagárselo.

I thank you from the bottom of my heart, I don't know how to repay you.

—Se lo agradezco en el alma. —No hay de qué, de verdad.

—I'm deeply grateful. —Don't mention it, truly.

Lo que hizo por mi familia, se lo agradezco en el alma.

What you did for my family — I'm deeply grateful.