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Lo que más me cuesta es...

What I find hardest is... / The most difficult thing for me is...

Sentence Frames
Notes & Usage:

Frame for expressing your greatest difficulty or challenge with something. Very useful in language learning and personal reflection.

See It in Context

Lo que más me cuesta es pronunciar la r.

What I find hardest is pronouncing the r.

Lo que más me cuesta es mantener la concentración por las tardes.

The most difficult thing for me is maintaining concentration in the afternoons.

—¿Qué te resulta difícil? —Lo que más me cuesta es el subjuntivo.

—What do you find difficult? —What I find hardest is the subjunctive.